I am a James S. McDonnell independent fellow at the Rockefeller University Center for Studies in Physics and Biology, developing computational methods for studying microbial ecology in the human gut and in the marine environment, and its contribution to human and environmental health.
Prior to this, I completed my Ph.D. at the Weizmann Institute of Science with Prof. Eran Segal, studying the human microbiome and its effect on host health and personalized nutrition.
News and updates
- I will be opening my own lab in September 2021, details coming soon!
- November 2020 - Our new paper is out in Science!
Address
Center for Studies in Physics and Biology
The Rockefeller University
1230 York Ave
New York, NY 10065
Phone
+1 (212) 327 8531
Environmental microbiology
Countless global processes rely on the workings of microbes, making them excellent indicators of environmental health and targets for intervention. I study the ability of natural microbial communities to undertake these roles using machine learning to combine multiple layers of environmental and microbial data.
Image source: Smithsonian Photo
Microbial genomics
The genetic repertoire of microbes is immense, enabling them to perform countless biochemical tasks. Microbes are typically hard to study, as most cannot be grown in the lab. I design new tools to study microbial genes sampled directly from their natural habitat and learn how they affect their environment.
Image source: University of California, San Diego
The human microbiome
Microbes in and on our body have been suggested to contribute to numerous disorders including diabetes, inflammatory bowel diseases and autism. In past and ongoing work I am developing methods aimed at exploring the role of the microbiome in metabolic disease and its mechanisms of action.
Image source: Elinav Lab, Weizmann Institute of Science
Selected publications Google Scholar
Resource conservation manifests in the genetic code PDF Journal
Liat Shenhav* and David Zeevi*^, Science 370 (6517), 683-687 (2020)
Perspective in Science by Polz and Cordero
Structural variation in the gut microbiome associates with host health PDF Journal
David Zeevi*^, Tal Korem*,Anastasia Godneva, Noam Bar, Alexander Kurilshikov, Maya Lotan-Pompan, Adina Weinberger, Jingyuan Fu, Cisca Wijmenga, Alexandra Zhernakova, Eran Segal^, Nature 568 (7750), 43-48 (2019)
Highlight in Nature Reviews Genetics, Nature Microbiology News & Views, Highlight in Molecular Cell
Personalized nutrition by prediction of glycemic responses PDF Journal
David Zeevi*, Tal Korem*, Niv Zmora*, David Israeli*, Daphna Rothschild, Adina Weinberger, Orly Ben-Yacov, Dar Lador, Tali Avnit-Sagi, Maya Lotan-Pompan, Jotham Suez, Jemal Ali Mahdi, Elad Matot, Gal Malka, Noa Kosower, Michal Rein, Gili Zilberman-Schapira, Lenka Dohnalová, Meirav Pevsner-Fischer, Rony Bikovsky, Zamir Halpern, Eran Elinav, Eran Segal, Cell 163 (5), 1079-1094 (2015)
Cover image for Cell, Video abstract, Nature, Time Magazine, NY Times, BBC, The Atlantic, Reddit AMA Series
Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples PDF Journal
Tal Korem*, David Zeevi*, Jotham Suez*, Adina Weinberger*, Tali Avnit-Sagi, Maya Pompan-Lotan, Elad Matot, Ghil Jona, Alon Harmelin, Nadav Cohen, Alexandra Sirota-Madi, Christoph A Thaiss, Meirav Pevsner-Fischer, Rotem Sorek, Ramnik J Xavier, Eran Elinav, Eran Segal, Science 349 (6252), 1101-1106 (2015)
Commentary in Science
Artificial sweeteners induce glucose intolerance by altering the gut microbiota PDF Journal
Jotham Suez, Tal Korem*, David Zeevi*, Gili Zilberman-Schapira*, Christoph A Thaiss, Ori Maza, David Israeli, Niv Zmora, Shlomit Gilad, Adina Weinberger, Yael Kuperman, Alon Harmelin, Ilana Kolodkin-Gal, Hagit Shapiro, Zamir Halpern, Eran Segal, Eran Elinav, Nature 514 (7521), 181 (2014)
Preview in Nature, The Economist, NY Times, Newsweek
Transkingdom control of microbiota diurnal oscillations promotes metabolic homeostasis PDF Journal
Christoph A Thaiss, David Zeevi, Maayan Levy, Gili Zilberman-Schapira, Jotham Suez, Anouk C Tengeler, Lior Abramson, Meirav N Katz, Tal Korem, Niv Zmora, Yael Kuperman, Inbal Biton, Shlomit Gilad, Alon Harmelin, Hagit Shapiro, Zamir Halpern, Eran Segal, Eran Elinav, Cell 159 (3), 514-529 (2014)
Bread affects clinical parameters and induces gut microbiome-associated personal glycemic responses PDF Journal
Tal Korem*, David Zeevi*, Niv Zmora, Omer Weissbrod, Noam Bar, Maya Lotan-Pompan, Tali Avnit-Sagi, Noa Kosower, Gal Malka, Michal Rein, Jotham Suez, Ben Z Goldberg, Adina Weinberger, Avraham A Levy, Eran Elinav, Eran Segal, Cell Metabolism 25 (6), 1243-1253 (2017)
Cover image for Cell Metabolism, The Atlantic, CNN
Additional publications
Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT Journal
Jotham Suez*, Niv Zmora*, Gili Zilberman-Schapira*, Uria Mor*, Mally Dori-Bachash, Stavros Bashiardes, Maya Zur, Dana Regev-Lehavi, Rotem Ben-Zeev Brik, Sara Federici, Max Horn, Yotam Cohen, Andreas E Moor, David Zeevi, Tal Korem, Eran Kotler, Alon Harmelin, Shalev Itzkovitz, Nitsan Maharshak, Oren Shibolet, Meirav Pevsner-Fischer, Hagit Shapiro, Itai Sharon, Zamir Halpern, Eran Segal, Eran Elinav, Cell 174 (6), 1406-1423 (2018)
Environment dominates over host genetics in shaping human gut microbiota Journal
Daphna Rothschild*, Omer Weissbrod*, Elad Barkan*, Alexander Kurilshikov, Tal Korem, David Zeevi, Paul I Costea, Anastasia Godneva, Iris N Kalka, Noam Bar, Smadar Shilo, Dar Lador, Arnau Vich Vila, Niv Zmora, Meirav Pevsner-Fischer, David Israeli, Noa Kosower, Gal Malka, Bat Chen Wolf, Tali Avnit-Sagi, Maya Lotan-Pompan, Adina Weinberger, Zamir Halpern, Shai Carmi, Jingyuan Fu, Cisca Wijmenga, Alexandra Zhernakova, Eran Elinav, Eran Segal, Nature 555 (7965), 210 (2018)
Microbiota diurnal rhythmicity programs host transcriptome oscillations Journal
Christoph A Thaiss*, Maayan Levy*, Tal Korem*, Lenka Dohnalová, Hagit Shapiro, Diego A Jaitin, Eyal David, Deborah R Winter, Meital Gury-BenAri, Evgeny Tatirovsky, Timur Tuganbaev, Sara Federici, Niv Zmora, David Zeevi, Mally Dori-Bachash, Meirav Pevsner-Fischer, Elena Kartvelishvily, Alexander Brandis, Alon Harmelin, Oren Shibolet, Zamir Halpern, Kenya Honda, Ido Amit, Eran Segal, Eran Elinav, Cell 167 (6), 1495-1510 (2016)
Talking about cross-talk: the immune system and the microbiome Journal
David Zeevi*, Tal Korem*, Eran Segal, Genome Biology 17 (1), 50 (2016)
Taking it personally: personalized utilization of the human microbiome in health and disease Journal
Niv Zmora*, David Zeevi*, Tal Korem*, Eran Segal, Eran Elinav, Cell host & microbe 19 (1), 12-20 (2016)
Microbiota-modulated metabolites shape the intestinal microenvironment by regulating NLRP6 inflammasome signaling Journal
Maayan Levy*, Christoph A Thaiss*, David Zeevi, Lenka Dohnalova, Gili Zilberman-Schapira, Jemal Ali Mahdi, Eyal David, Alon Savidor, Tal Korem, Yonatan Herzig, Meirav Pevsner-Fischer, Hagit Shapiro, Anette Christ, Alon Harmelin, Zamir Halpern, Eicke Latz, Richard A Flavell, Ido Amit, Eran Segal, Eran Elinav, Cell 163 (6), 1428-1443 (2015)
A day in the life of the meta-organism: diurnal rhythms of the intestinal microbiome and its host Journal
Christoph A Thaiss*, David Zeevi*, Maayan Levy*, Eran Segal, Eran Elinav, Gut microbes 6 (2), 137-142 (2015)
Phosphatidylserine increases IKBKAP levels in a humanized knock-in IKBKAP mouse model Journal
Ron Bochner, Yael Ziv, David Zeevi, Maya Donyo, Lital Abraham, Ruth Ashery-Padan, Gil Ast, Human molecular genetics 22 (14), 2785-2794 (2013)
The operonic location of auto-transcriptional repressors is highly conserved in bacteria Journal
Nimrod D Rubinstein*, David Zeevi*, Yaara Oren, Gil Segal, Tal Pupko, Molecular biology and evolution 28 (12), 3309-3318 (2011)
Phosphatidylserine increases IKBKAP levels in familial dysautonomia cells Journal
Hadas Keren, Maya Donyo, David Zeevi, Channa Maayan, Tal Pupko, Gil Ast, PLoS One 5 (12), e15884 (2010)